Awakening dormant genes with cancer drugs

Here?s one that first appeared online at the end of last year by Benjamin Philpot, Bryan Roth and Mark Zylka about a finding that could lead to a therapy for Angelman Syndrome. Angelman syndrome is a rare neurodevelopmental disorder affecting 1 in 15,000 live births and is characterized by developmental delay, lack of speech, seizures, and motor difficulties. There are no therapies available for core symptoms and individuals generally require care throughout life. Autism is often diagnosed in Angelman Syndrome individuals, and the same genomic region has been fingered as a culprit in both disorders. Angelman Syndrome is most commonly caused by deletion of a region on the maternal copy of chromosome 15 containing the gene UBE3A, conversely, some forms of autism may also be caused by duplication of this region.  Read more

Source: http://feeds.nature.com/~r/nn/rss/action_potential/~3/kiyeOHlcVvs/awakening-dormant-genes-with-cancer-drugs.html

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New edition: Cognition, Brain and Consciousness

Yes, now it’s out as a second edition. The big cognitive neuroscience textbook entitled “Cognition, Brain and Consciousness” is edited by Bernard J. Baars and Nicole Gage, and has already received good reviews, among one prominent and positive review in Nature Neuroscience. (Both my chapters survived the revision process, with minor changes.) I’ve been using [...]

Source: http://brainethics.wordpress.com/2010/06/18/new-edition-cognition-brain-and-consciousness/

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